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摘要
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A 63-year-old woman presents with a 1-year history of a chronic dry cough, associated with a sensation of irritation in the throat. Prolonged bouts of coughing are associated with stress urinary incontinence and occasionally end with retching and vomiting. The cough is triggered by changes in temperature, strong smells (e.g., the smell of cleaning products), laughing, and prolonged talking. She has no notable medical history, reports being otherwise well, and does not smoke. She has been prescribed a bronchodilator and inhaled and nasal glucocorticoids, but has had no benefit from any of these. The results of a physical examination, chest radiography, and spirometry are normal. How would you further evaluate and manage this condition?
Keyword:
GASTROESOPHAGEAL-REFLUX DISEASE
REFRACTORY CHRONIC COUGH
LARYNGOPHARYNGEAL REFLUX
CLINICAL-FEATURES
CHEST GUIDELINE
BILE-ACIDS
MANAGEMENT
DIAGNOSIS
THERAPY
MANIFESTATION
AI总结
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期刊
IF:
78.5
论文数:
2.7W
被引数:
45.8W
机构
引用论文
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LANCET
IF88.5
P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 studyP2X3受体拮抗剂 (AF-219) 治疗难治性慢性咳嗽: 一项随机、双盲、安慰剂对照2期研究
LANCET
IF88.5
Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia
Neuroscience
IF0
Chronic cough due to gastroesophageal reflux disease - ACCP evidence-based clinical practice guidelines胃食管反流病所致慢性咳嗽-ACCP循证临床实践指南
CHEST
IF8.6

