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Clinical and quality of life predictors in patients with schizophrenia with and without substance use disorder
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DOI：10.1016/j.pnpbp.2026.111734.png)
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Abstract
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• SZ, SZ+, and SUD patients present distinct clinical and QoL profiles. • The SZ+ group shows high suicide risk and the worst social QoL of all groups. • Atypical antipsychotics and nicotine dependence are key predictors factors. • A machine learning model classified the groups with 97.1% accuracy.
Keywords:
schizophrenia
substance use disorder
quality of life
suicide risk
machine learning
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