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Clinical Importance of All the Characteristics of Late Gadolinium Enhancement from Acquisition to Expert and Artificial Intelligence Analysis: State-of-the-Art
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DOI：10.1016/j.jocmr.2026.102764.png)
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Abstract
En 中文
Late gadolinium enhancement (LGE) assessed by cardiovascular magnetic resonance is the cornerstone in the assessment of myocardial tissue characterization, providing crucial diagnostic and prognostic information across a wide spectrum of cardiac conditions. While LGE is traditionally evaluated for its presence and extent, a comprehensive assessment of its diverse characteristics, called “LGE granularity”—including its location, extent, and pattern—offers deeper insights into myocardial pathophysiology.
Keywords:
AI
artificial intelligence
AL
amyloid light chain
AUC
area under the curve
CAD
coronary artery disease
CMR
cardiovascular magnetic resonance
DCM
dilated cardiomyopathy
DICOM
Digital Imaging and Communications in Medicine
DSP
desmoplakin
EMIDEC
Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRI
ESC
European Society of Cardiology
FLNC
filamin C
FWHM
full width at half maximum
HCM
hypertrophic cardiomyopathy
ICD
implantable cardioverter-defibrillator
ICM
ischemic cardiomyopathy
IMD
inflammatory myocardial diseases
LGE
late gadolinium enhancement
LMNA
lamin A/C
LV
left ventricle
LVEF
left ventricular ejection fraction
ML
machine learning
MRI
magnetic resonance imaging
NDLVC
non-dilated left ventricular cardiomyopathy
NICM
non-ischemic cardiomyopathy
PKP2
plakophilin-2
PSIR
phase-sensitive inversion recovery
ROI
region of interest
RV
right ventricle
SCD
sudden cardiac death
SCMR
Society of Cardiovascular Magnetic Resonance
SD
standard deviation
SSFP
steady-state free precession
T1
longitudinal relaxation time
TI
inversion time
TTN
titin
VT
ventricular tachycardia
Review
cardiovascular magnetic resonance
late gadolinium enhancement
artificial intelligence
cardiomyopathies
acquisition
imaging protocol
standardized analysis
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