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Clinical Trial: Predicting Response to Iron Therapy in Patients With Active Inflammatory Bowel Disease Using Hepcidin and Functional Iron Indices: A Multicentre Randomised Trial

delete2026-07-30
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OA
AI
L
Lola J. M. Koppelman
R
Roberta Loveikyte
R
Rogier L. Goetgebuer
S
Sander van der Marel
A
Annemarie C. de Vries
G
Gerard Dijkstra
A
Andrea E. van der Meulen‐de Jong *
T
the Dutch Iron Study Group
DOI:10.1111/apt.70775delete
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Abstract

Abstract

En 中文
Iron deficiency anaemia (IDA) is common in inflammatory bowel disease (IBD) and impairs quality of life. Hepcidin, the regulator of systemic iron homeostasis, may predict response to iron therapy; however, its utility in IBD remains unclear. This study evaluated whether baseline hepcidin predicts response to oral and intravenous (IV) iron in active IBD to guide personalised treatment.
Keywords:
anaemia
hepcidin
inflammatory bowel disease
iron deficiency
iron therapy
personalised medicine
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A
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
IF:
6.7
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422
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0

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L
leiden university medical center
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H
haaglanden medical center
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university of groningen
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Erasmus University Medical Center
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amsterdam university medical center
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