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Colchicine induces developmental defects and renal toxicity in zebrafish by upregulating the oxidative stress
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DOI：10.1016/j.cbpc.2025.110328.png)
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Abstract
En 中文
• Colchicine induces toxicity in zebrafish embryonic development. • Colchicine induces nephrotoxicity in juvenile and adult zebrafish. • Colchicine exposure upregulates the oxidative stress signaling pathway. • Astaxanthin can ameliorate colchicine-induced abnormal renal developmental and renal toxicity by downregulating oxidative stress.
Keywords:
colchicine
zebrafish
nephrotoxicity
oxidative stress
astaxanthin
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