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Command'' surfaces with thermo-switchable antibacterial activity
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DOI：10.1016/j.msec.2019.109806.png)
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摘要
En 中文
In the presented work smart antibacterial surfaces based on silver nanoparticles (AgNPs) embedded in temperature-responsive poly(di(ethylene glycol)methyl ether methacrylate) - (POEGMA188) as well as poly(4-vi-nylpyridine) (P4VP) coatings attached to a glass surface were successfully prepared. The composition, thickness, morphology and wettability of the resulting coatings were analyzed using ToF-SIMS, XPS, EDX, ellipsometry, AFM, SEM and CA measurements, respectively. Temperature-switched killing of the bacteria was tested against Escherichia coli ATCC 25922 (representative of Gram-negative bacteria) and Staphylococcus aureus ATCC 25923 (representative of Gram-positive bacteria) at 4 and 37 degrees C. In general at 4 degrees C no significant difference was observed between the amounts of bacteria accounted on the grafted brush coatings and within the control sample. In contrast, at 37 degrees C almost no bacteria were visible for temperature-responsive coating with AgNPs, whereas the growth of bacteria remains not disturbed for pure coating, indicating strong temperature-dependent antibacterial properties of AgNPs integrated into brushes.
Keyword:
Grafted polymer brushes
Antibacterial
Silver nanoparticles
Smart surface
Temperature-responsive
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M
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8.1
论文数:
6.0K
被引数:
5.5W
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