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Comparative effects of four immunostimulants on immunity, antioxidant capacity and intestinal microbiota of juvenile Coreius guichenoti: A preliminary screening
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DOI：10.1016/j.aqrep.2026.103725.png)
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Abstract
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• First evaluation of four immunostimulants in critically endangered Coreius guichenoti. • Bacillus coagulans CICC 20138 enhances immunity, antioxidants and gut health. • Probiotic downregulates enterobacterial common antigen biosynthesis pathway. • Reduced pathogenic Plesiomonas, Shigella and Aeromonas in intestinal microbiota. • Provides a basis for dose‑response studies in conservation aquaculture.
Keywords:
Largemouth bronze gudgeon
Bacillus coagulans
Oxidative stress
Immune response
Intestinal microbiota
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