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Comparative transcriptomics of immune response to viral and bacterial stimuli in three acanthopterygian bony fish
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DOI：10.1016/j.fsi.2026.111375.png)
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Abstract
En 中文
• TLR signalling is emerging as a conserved pathway in all species and conditions. • The viral mimic Poly I:C induces more conserved responses than Vibrio. • Seven orthologous genes show uniform regulation across all stimuli/conditions. • In vitro responses are dominated by PRRs, while in vivo enriches DNA repair. • Comparative analysis identifies chemokine, interferon, APP, signalling & MAPK genes.
Keywords:
Immune response
RNA-seq
Vibrio anguillarum
Poly I:C
Turbot
Gilthead seabream
European seabass
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