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摘要
En 中文
Fast-acting nourotransmitters can exit the synaptic cleft and bind to extrasynaptic receptors. This process is modulated by transmitter uptake mechanisms (transporters). A new study focusing on glutamate-mediated transmission In the cerebellum describes the specific role of neuronal transporters in modulating the access of glutamate to extrasynaptic metabotropic glutamate receptors, and reveals Important consequences of extrasynaptic signaling on synaptic plasticity.
Keyword:
METABOTROPIC GLUTAMATE RECEPTORS
CEREBELLAR PURKINJE-CELLS
LONG-TERM DEPRESSION
PARALLEL FIBER
TRANSPORTERS
SYNAPSES
GABA
LOCALIZATION
HIPPOCAMPUS
SPILLOVER
AI总结
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