Complement

Paul A. Monach

doi:10.1002/art.42671

2023-10-16

PRE

Paul A. Monach *

DOI：10.1002/art.42671

原文链接

摘要

En 中文

The role of complement in human autoimmune, inflammatory, and infectious diseases is reviewed, focusing on clinical applicability. A typical case is presented in which serum testing for C3 and C4 is performed to help assess a syndrome with a broad differential diagnosis. The review includes a discussion of complement deficiency states, consumption of complement by diseases characterized by immune-complex formation and deposition, usefulness and interpretation of laboratory tests for complement, and development of drugs targeting specific components of the complement pathway for a growing number of indications.

Keyword:

VASCULITIS

ACTIVATION

期刊

Arthritis and Rheumatology

IF:

10.9

论文数:

4.5K

被引数:

2.2W

机构

US Department of Veterans Affairs

学者数:

107

论文数: 55

被引数: 0

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