.png){kind=icon}
返回
Complex-valued scatter compensation in nonlinear microscopy
.png){kind=icon}
OA
AI
DOI：10.1103/PhysRevApplied.22.044036.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Nonlinear, i.e., multiphoton microscopy is a powerful technique for imaging deep into biological tissues. Its penetration depth can be increased further using adaptive optics. In this work, we present a fast, feedback-based adaptive-optics algorithm, termed C-DASH, for multiphoton imaging through multiplescattering media. C-DASH utilizes complex-valued light shaping (i.e., joint shaping of amplitude and phase), which offers several advantages over phase-only techniques: it converges faster, it delivers higher image quality enhancement, it shows a robust performance largely insensitive to the axial position of the correction plane, and it has a higher ability to cope with, on the one hand, scattering media that vary over time and, on the other hand, scattering media that are partially absorbing. Furthermore, our method is practically self-aligning. We also present a simple way to implement C-DASH using a single reflection off a phase-only spatial light modulator. We provide a thorough characterization of our method, presenting results of numerical simulations as well as two-photon excited fluorescence imaging experiments.
Keyword:
ADAPTIVE OPTICS
FOCUSING LIGHT
PHASE
MEDIA
期刊
IF:
4.4
论文数:
7.1K
被引数:
2.8W
机构
引用论文
分享收藏Focusing light through dynamical samples using fast continuous wavefront optimization.png)
OPTICS LETTERS
OAAI
OPTICS LETTERSIF3.3
OAAI分享收藏Focusing light inside dynamic scattering media with millisecond digital optical phase conjugationOPTICAOAAI
OPTICAIF8.5
OAAI分享收藏分享收藏Shack-Hartmann wavefront-sensor-based adaptive optics system for multiphoton microscopy基于shack-hartmann波前传感器的多光子显微自适应光学系统OAAI
OAAI分享收藏Numerical study of multi-conjugate large area wavefront correction for deep tissue microscopyOPTICS EXPRESSOAAI
OPTICS EXPRESSIF3.3
OAAI分享收藏
查看更多内容