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Contributions of 2-h post-load glucose, fasting blood glucose and glycosylated haemoglobin elevations to the prevalence of diabetes and pre-diabetes in adults: A systematic analysis of global data
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DOI：10.1111/dom.70130.png)
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Abstract
En 中文
Some studies found that the association of fasting blood glucose (FPG) or glycosylated haemoglobin (HbA1c) elevation with diabetic complications was not statistically significant after controlling for the confounding caused by 2-h post-load glucose (2hPG) elevation. Furthermore, inclusion of HbA1c as a diagnostic measure for diabetes has raised some concerns about over-diagnosis and over-treatment. This study aimed to quantify the contributions of 2hPG, FPG and HbA1c elevations to the prevalence of diabetes and pre-diabetes respectively, by synthesising global data, which can serve as essential parameters in cost-effectiveness analysis and inform updates of practice guidelines about prevention and control of diabetes.
Keywords:
2-h post-load glucose
diabetes
fasting blood glucose
glycosylated haemoglobin
pre-diabetes
prevalence
systematic review
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