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CortexODE: Learning Cortical Surface Reconstruction by Neural ODEs
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DOI：10.1109/TMI.2022.3206221.png)
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摘要
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We present CortexODE, a deep learning framework for cortical surface reconstruction. CortexODE leverages neural ordinary differential equations (ODEs) to deform an input surface into a target shape by learning a diffeomorphic flow. The trajectories of the points on the surface are modeled as ODEs, where the derivatives of their coordinates are parameterized via a learnable Lipschitz-continuous deformation network. This provides theoretical guarantees for the prevention of self-intersections. CortexODE can be integrated to an automatic learning-based pipeline, which reconstructs cortical surfaces efficiently in less than 5 seconds. The pipeline utilizes a 3D U-Net to predict a white matter segmentation from brain Magnetic Resonance Imaging (MRI) scans, and further generates a signed distance function that represents an initial surface. Fast topology correction is introduced to guarantee homeomorphism to a sphere. Following the isosurface extraction step, two CortexODE models are trained to deform the initial surface to white matter and pial surfaces respectively. The proposed pipeline is evaluated on large-scale neuroimage datasets in various age groups including neonates (25-45 weeks), young adults (22-36 years) and elderly subjects (55-90 years). Our experiments demonstrate that the CortexODE-based pipeline can achieve less than 0.2mm average geometric error while being orders of magnitude faster compared to conventional processing pipelines.
Keyword:
Surface reconstruction
Surface treatment
Pipelines
Surface morphology
Image reconstruction
Magnetic resonance imaging
Strain
Brain MRI
cortical surface reconstruction
geometric deep learning
neural ODE
期刊
IF:
9.8
论文数:
6.3K
被引数:
3.7W
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Unsupervised learning of probabilistic diffeomorphic registration for images and surfaces.png)
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