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Crashing by design: Utilizing DNA damage for MCC differentiation
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DOI：10.1016/j.tcb.2026.06.002.png)
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Abstract
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Multiciliated cells (MCCs) represent a complex cell type with a range of unique features. Jewett et al . identify a novel DNA damage response (DDR) that occurs during MCC differentiation. Inhibition of DDR blocks the formation of MCCs, indicating that this damage response is likely an important step in MCC differentiation.
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