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Crystal Shape Engineering

delete2008-11-13
delete334
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OA
AI
M
Michael A. Lovette
A
Andrea Browning
D
Derek W. Griffin
J
Jacob P. Sizemore
R
Ryan C. Snyder
M
Michael F. Doherty *
DOI:10.1021/ie800900fdelete
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摘要

摘要

En 中文
In an industrial crystallization process, crystal shape strongly influences end-product quality and functionality, as well as downstream processing. In addition, nucleation events, solvent effects, and polymorph selection play critical roles in both the design and operation of a crystallization plant and the patentability of the product and process. Therefore, investigation of these issues, with respect to a priori prediction, is (and will continue to be) an important avenue of research. In this review, we discuss the state-of-the-art in modeling crystallization processes over a range of length scales relevant to nucleation through process design. We also identify opportunities for continued research and specific areas where significant advancements are needed.
Keyword:
ATOMIC-FORCE MICROSCOPY
POPULATION BALANCE-EQUATIONS
L-GLUTAMIC ACID
MULTIDIMENSIONAL CRYSTALLIZATION PROCESSES
INDUSTRIAL BATCH CRYSTALLIZATION
TAILOR-MADE ADDITIVES
IN-SITU
IMAGE-ANALYSIS
POLYMORPHIC TRANSFORMATION
GROWTH-KINETICS

期刊

I
Industrial and Engineering Chemistry Research
IF:
3.9
论文数:
4.0W
被引数:
9.6W

机构

University of California System 封面图
University of California System
学者数:
37.7W
论文数: 33.8W
被引数: 6.6K
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