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CyberArc: a non-coplanar-arc optimization algorithm for CyberKnife

delete2017-06-26
delete17
PRE
AI
V
Vasant Kearney *
J
J Cheung
C
Christopher McGuinness
T
Timothy D. Solberg
DOI:10.1088/1361-6560/aa6f92delete
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摘要

摘要

En 中文
The goal of this study is to demonstrate the feasibility of a novel non-coplanar- arc optimization algorithm (CyberArc). This method aims to reduce the delivery time of conventional CyberKnife treatments by allowing for continuous beam delivery. CyberArc uses a 4 step optimization strategy, in which nodes, beams, and collimator sizes are determined, source trajectories are calculated, intermediate radiation models are generated, and final monitor units are calculated, for the continuous radiation source model. The dosimetric results as well as the time reduction factors for CyberArc are presented for 7 prostate and 2 brain cases. The dosimetric quality of the CyberArc plans are evaluated using conformity index, heterogeneity index, local confined normalized-mutual-information, and various clinically relevant dosimetric parameters. The results indicate that the CyberArc algorithm dramatically reduces the treatment time of CyberKnife plans while simultaneously preserving the dosimetric quality of the original plans.
Keyword:
optimization
CyberKnife
arc therapy
non-coplaner
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期刊

Physics in Medicine and Biology 封面图
Physics in Medicine and Biology
IF:
3.4
论文数:
1.4W
被引数:
3.1W

机构

University of California System 封面图
University of California System
学者数:
37.7W
论文数: 33.8W
被引数: 6.6K
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