.png){kind=icon}
返回
Cyclodextrin Multicomponent Complexes: Pharmaceutical Applications
.png){kind=icon}
OA
AI
DOI：10.3390/pharmaceutics13071099.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely used as carriers in the pharmaceutical industry for their ability to modulate several properties of drugs through the formation of drug-CD complexes. The addition of an auxiliary substance when forming multicomponent complexes is an adequate strategy to enhance complexation efficiency and to facilitate the therapeutic applicability of different drugs. This review discusses multicomponent complexation using amino acids; organic acids and bases; and water-soluble polymers as auxiliary excipients. Special attention is given to improved properties by including information on the solubility, dissolution, permeation, stability and bioavailability of several relevant drugs. In addition, the use of multicomponent CD complexes to enhance therapeutic drug effects is summarized.
Keyword:
auxiliary agents
complexation efficiency amino acids
organic acids
organic bases
water-soluble polymers
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
5.5
论文数:
1.5W
被引数:
6.2W
机构
引用论文
Amidated pectin-based wafers for econazole buccal delivery: Formulation optimization and antimicrobial efficacy estimation.png)
CARBOHYDRATE POLYMERS
CARBOHYDRATE POLYMERSIF12.5
PREAI
分享收藏
查看更多内容