.png){kind=icon}
.png){kind=icon}
Return
Cytogenetic and Molecular Analysis of a “Double-Hit” RUNX1 Including a RUNX1 p.Trp279* and a Cryptic Novel t(6;21)(q25;q22)/RUNX1::ARID1B in Acute Myeloid Leukemia
.png){kind=icon}
OA
AI
R
J
L
K
S
O
F
W
P
DOI：10.1002/gcc.70148.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
Alterations involving RUNX1 are recurrent in hematologic malignancies and contribute to disease pathogenesis via dysregulation of transcriptional factors essential for hematopoiesis. Here, we report an acquired alteration in both alleles of RUNX1; one is a truncating mutation and the second is a novel RUNX1::ARID1B identified in acute myeloid leukemia.
Journal
G
IF:
0
Papers:
24
Citations:
0
Organization
Cited Papers