.png){kind=icon}
返回
dcSBM: A federated constrained source-based morphometry approach for multivariate brain structure mapping
.png){kind=icon}
OA
AI
DOI：10.1002/hbm.26483.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The examination of multivariate brain morphometry patterns has gained attention in recent years, especially for their powerful exploratory capabilities in the study of differences between patients and controls. Among the many existing methods and tools for the analysis of brain anatomy based on structural magnetic resonance imaging data, data-driven source-based morphometry (SBM) focuses on the exploratory detection of such patterns. Here, we implement a semi-blind extension of SBM, called constrained source-based morphometry (constrained SBM), which enables the extraction of maximally independent reference-alike sources using the constrained independent component analysis (ICA) approach. To do this, we combine SBM with a set of reference components covering the full brain, derived from a large independent data set (UKBiobank), to provide a fully automated SBM framework. This also allows us to implement a federated version of constrained SBM (cSBM) to allow analysis of data that is not locally accessible. In our proposed decentralized constrained source-based morphometry (dcSBM), the original data never leaves the local site. Each site operates constrained ICA on its private local data using a common distributed computation platform. Next, an aggregator/master node aggregates the results estimated from each local site and applies statistical analysis to estimate the significance of the sources. Finally, we utilize two additional multisite patient data sets to validate our model by comparing the resulting group difference estimates from both cSBM and dcSBM.
Keyword:
federated learning
neuroimaging
SBM
sMRI
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.3
论文数:
6.8K
被引数:
2.6W
机构
暂无机构信息
引用论文
Semiblind Spatial ICA of fMRI Using Spatial Constraints使用空间约束的fMRI半盲空间ICA.png)
HUMAN BRAIN MAPPINGOAAI
HUMAN BRAIN MAPPINGIF3.3
OAAI分享收藏Depletion of NK Cells Resistant to Ionizing Radiation Increases Mutations in Mice After Whole-body IrradiationIn Vivo
OAAI
In VivoIF0
OAAI分享收藏
查看更多内容