Decellularized dermal scaffold biofunctionalized with quercetin nanoparticles enhances angiogenesis and attenuates inflammation in type 2 diabetic wounds

Ahmed Hjazi

doi:10.1016/j.tice.2026.103562

Decellularized dermal scaffold biofunctionalized with quercetin nanoparticles enhances angiogenesis and attenuates inflammation in type 2 diabetic wounds

2026-04-29

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Ahmed Hjazi

DOI：10.1016/j.tice.2026.103562

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• Quercetin-functionalized dermal scaffold accelerates diabetic wound healing. • Bioengineered scaffold enhances angiogenesis in type 2 diabetic wounds. • Treatment reduces inflammation and improves regenerative remodeling. • Antioxidant defense increased (GSH, SOD, CAT) while MDA decreased. • Scaffold improves collagen density and biomechanical strength.

Keywords:

Quercetin

Dermal scaffold

Angiogenesis

Diabetic wounds

Inflammation

Decellularized dermal scaffold biofunctionalized with quercetin nanoparticles enhances angiogenesis and attenuates inflammation in type 2 diabetic wounds

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