Decoupling sequence and structure

Chuanliu Wu

doi:10.1038/s41570-025-00726-2

2025-05-29

PRE

Chuanliu Wu

DOI：10.1038/s41570-025-00726-2

原文链接

摘要

En 中文

1961年，研究表明，核糖核酸酶可以在空气氧化下从完全还原和变性的多肽链正确折叠。自那时以来，调控多肽链氧化折叠的原理已得到阐明，我们控制这一过程的能力也取得了显著进步。

期刊

Nature Reviews Chemistry

IF:

51.7

论文数:

1.0K

被引数:

1.6W

机构

MOE Key Laboratory of Spectrochemical Analysis and Instrumentation

学者数:

论文数: 1

被引数: 0

引用论文

Motif-Directed Oxidative Folding to Design and Discover Multicyclic Peptides for Protein Recognition Motif-导向氧化折叠法设计与发现用于蛋白质识别的多环肽

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2025-03-14

PREAI

Wu, CL

Reagentless Oxidative Folding of Disulfide-Rich Peptides Catalyzed by an Intramolecular Diselenide

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2012-03-27

OAAI

Steiner, Andrew M.; Woycechowsky, Kenneth J.; Olivera, Baldomero M.; Bulaj, Grzegorz

Twin disulfides for orthogonal disulfide pairing and the directed folding of multicyclic peptides

NATURE CHEMISTRY

IF20.2

2012-10-28

PREAI

Wu, Chuanliu; Leroux, Jean-Christophe; Gauthier, Marc A.

THE KINETICS OF FORMATION OF NATIVE RIBONUCLEASE DURING OXIDATION OF THE REDUCED POLYPEPTIDE CHAIN

Proceedings of the National Academy of Sciences

IF0

1961-09-01

OAAI

C. B. Anfinsen; E. Haber; M. Sela; F. H. White

Disulfide Bond Mimetics: Strategies and Challenges

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2017-08-23

PREAI

Gori, Alessandro; Gagni, Paola; Rinaldi, Silvia

Directed Disulfide Pairing and Folding of Peptides for the De Novo Development of Multicyclic Peptide Libraries

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-09-11

PREAI

Lu, Shuaimin; Wu, Yapei; Li, Jinjing; Meng, Xiaoting; Hu, Chenliang; Zhao, Yibing; Wu, Chuanliu

Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets

NATURE COMMUNICATIONS

IF15.7

2017-12-21

OAAI

Crook, Zachary R.; Sevilla, Gregory P.; Friend, Della; Brusniak, Mi-Youn; Bandaranayake, Ashok D.; Clarke, Midori; Gewe, Mesfin; Mhyre, Andrew J.; Baker, David; Strong, Roland K.; Bradley, Philip; Olson, James M.

Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-01-12

PREAI

Lu, Shuaimin; Fan, Shihui; Xiao, Shuling; Li, Jinjing; Zhang, Shilong; Wu, Yapei; Kong, Chuilian; Zhuang, Jie; Liu, Hongtan; Zhao, Yibing; Wu, Chuanliu

Accurate de novo design of hyperstable constrained peptides 超稳定约束肽的精确从头设计

Nature

IF48.5

2016-09-14

PREAI

Gaurav Bhardwaj; Vikram Khipple Mulligan; Christopher D. Bahl; Jason M. Gilmore; Peta J. Harvey; Olivier Cheneval; Garry W. Buchko; Surya V. S. R. K. Pulavarti; Quentin Kaas; Alexander Eletsky; Po-Ssu Huang; William A. Johnsen; Per Jr Greisen; Gabriel J. Rocklin; Yifan Song; Thomas W. Linsky; Andrew Watkins; Stephen A. Rettie; Xianzhong Xu; Lauren P. Carter; Richard Bonneau; James M. Olson; Evangelos Coutsias; Colin E. Correnti; Thomas Szyperski; David J. Craik; David Baker

Protein folding and misfolding 蛋白质折叠和错误折叠

Nature

IF48.5

2003-12-01

PREAI

Christopher M. Dobson

没有更多内容