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Decrease in fMRI brain activation during working memory performed after sleeping under 10 lux light

delete2016-11-09
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AI
S
Seung‐Gul Kang
H
Ho‐Kyoung Yoon
C
Chul‐Hyun Cho
S
Soonwook Kwon
J
June Kang
Y
Young-Min Park
E
Eunil Lee
L
Leen Kim
H
Heon‐Jeong Lee *
DOI:10.1038/srep36731delete
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En 中文
The aim of this study was to investigate the effect of exposure to dim light at night (dLAN) when sleeping on functional brain activation during a working-memory tasks. We conducted the brain functional magnetic resonance imaging (fMRI) analysis on 20 healthy male subjects. All participants slept in a polysomnography laboratory without light exposure on the first and second nights and under a dim-light condition of either 5 or 10 lux on the third night. The fMRI scanning was conducted during n-back tasks after second and third nights. Statistical parametric maps revealed less activation in the right inferior frontal gyrus (IFG) after exposure to 10-lux light. The brain activity in the right and left IFG areas decreased more during the 2-back task than during the 1- or 0-back task in the 10-lux group. The exposure to 5-lux light had no significant effect on brain activities. The exposure to dLAN might influence the brain function which is related to the cognition.
Keyword:
EXPOSURE
RESPONSES
DEPRIVATION
MELATONIN
NIGHT
HUMANS
TASK
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