.png){kind=icon}
返回
Default Network Connectivity During a Working Memory Task
.png){kind=icon}
OA
AI
DOI：10.1002/hbm.21090.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The default network exhibits correlated activity at rest and has shown decreased activation during performance of cognitive tasks. There has been little investigation of changes in connectivity of this network during task performance. In this study, we examined task-related modulation of connectivity between two seed regions from the default network posterior cingulated cortex (PCC) and medial prefrontal cortex (mPFC) and the rest of the brain in 12 healthy adults. The purpose was to determine (1) whether connectivity within the default network differs between a resting state and performance of a cognitive (working memory) task and (2) whether connectivity differs between these nodes of the default network and other brain regions, particularly those implicated in cognitive tasks. There was little change in connectivity with the other main areas of the default network for either seed region, but moderate task-related changes in connectivity occurred between seed regions and regions outside the default network. For example, connectivity of the mPFC with the right insula and the right superior frontal gyrus decreased during task performance. Increased connectivity during the working memory task occurred between the PCC and bilateral inferior frontal gyri, and between the mPFC and the left inferior frontal gyrus, cuneus, superior parietal lobule, middle temporal gyrus and cerebellum. Overall, the areas showing greater correlation with the default network seed regions during task than at rest have been previously implicated in working memory tasks. These changes may reflect a decrease in the negative correlations occurring between the default and task-positive networks at rest. Hum Brain Mapp 32: 1029-1035, 2011. (C) 2010Wiley-Liss, Inc.
Keyword:
working memory
fMRI
default mode network
posterior cingulate
medial prefrontal cortex
insula
cognition
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.3
论文数:
6.8K
被引数:
2.6W
机构
引用论文
Functional Connectivity of Default Mode Network Components: Correlation, Anticorrelation, and Causality.png)
HUMAN BRAIN MAPPINGOAAI
HUMAN BRAIN MAPPINGIF3.3
OAAI分享收藏The human brain is intrinsically organized into dynamic, anticorrelated functional networks人类的大脑本质上是组织成动态的，反相关的功能网络OAAI
OAAI分享收藏Shortage of intensive care specialists in the United States: recent insights and proposed solutions
OAAI
OAAI分享收藏
查看更多内容