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Design for a binary synapse
DOI:10.1016/S0896-6273(04)00044-3.png)
摘要
En 中文
The mammalian rod transfers a binary signal, the capture of 0 or 1 photon. In this issue of Neuron, Sampath and Rieke show in mouse that the rod's tonic exocytosis in darkness completely saturates a G protein cascade to close nearly all postsynaptic channels. A full-sized photon event supresses exocytosis sufficiently to allow similar to30 postsynaptic channels to open simultaneously. Thus, the synapse behaves like a digital gate, whose hallmark is reliability and resistance to noise.
Keyword:
BIPOLAR CELLS
RETINA
RODS
SENSITIVITY
NOISE
CAT
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