.png){kind=icon}
.png){kind=icon}
Return
Development of angiostatin based radiopharmaceutical as a sensitive tool for detection of ATP synthase during acute vascular damage
.png){kind=icon}
OA
AI
A
T
C
B
J
H
G
DOI：10.1016/j.nucmedbio.2026.109633.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• First use of [89Zr]Zr-ANG to assess 72 h progression of ozone and LPS induced acute oxidative stress. • Uptake of [89Zr]Zr-ANG is specific to endothelial cell and platelet ATP synthase subunit β (ATPβ). • Higher [89Zr]Zr-ANG uptake observed in oxidatively stressed aorta and platelets; potential implications in platelet budding and ATP signaling. • Supports the use of [89Zr]Zr-ANG in chronic oxidative stress induced animal disease models.
Keywords:
Angiostatin
Oxidative stress
89Zr PET
Platelets
ATP synthase
IF1
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
3
Papers:
3.7K
Citations:
3.2K
Organization
Cited Papers