Diaphragm stimulation after human spinal cord injury: Effects on respiratory function and diaphragm muscle activation

Vose, Alicia K. PhD

doi:10.1097/TA.0000000000005085

Diaphragm stimulation after human spinal cord injury: Effects on respiratory function and diaphragm muscle activation

2026-06-08

0

PRE

AI

V

Vose, Alicia K. PhD

C

Cavka, Kathryn DPT

F

Freeborn, Paul BS

T

Tonuzi, Geneva MD

K

Kerwin, Andrew J. MD

Y

Yorkgitis, Brian K. DO

F

Fuller, David PhD

D

D’Alessandro, Alison DPT

W

Wauneka, Clayton N. PhD

C

Croft, Chasen MD

E

Emily J. Fox

DOI：10.1097/TA.0000000000005085

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Abstract

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Respiratory dysfunction is a leading cause of morbidity and mortality after cervical spinal cord injury (C-SCI). Respiratory impairment is exacerbated by mechanical ventilation, which is associated with higher infection rates and diaphragm atrophy. Intramuscular stimulation of the diaphragm, that is, diaphragm pacing (DP), is a potential strategy to facilitate ventilator weaning, enhance respiratory function, and reduce complications. However, its impact on respiratory recovery and neuromuscular activation remains understudied.

Keywords:

Cervical spinal cord injury

diaphragm pacing

respiratory function

ventilator weaning

rehabilitation

Diaphragm stimulation after human spinal cord injury: Effects on respiratory function and diaphragm muscle activation

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