Diffraction-based assay for detecting multiple analytes

doi:10.1007/s00216-002-1478-5

Diffraction-based assay for detecting multiple analytes

2002-09-01

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DOI：10.1007/s00216-002-1478-5

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The principles of diffraction are utilized to enable the simultaneous detection of multiple analytes in solution, forming the basis of a multi-analyte sensor. Probe molecules are immobilized on a substrate such that each type of molecule defines a specific pattern within the same region of substrate. The binding of a target molecule to its complementary probe is heralded by a characteristic diffraction image. This principle is demonstrated using antibody conjugates.

Keyword:

biosensor

diffraction

immunoassay

micro-contact printing

multi-analyte

Diffraction-based assay for detecting multiple analytes

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