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Diffusion abnormalities associated with brain arteriolosclerosis: An in-vivo MRI and pathology study in community-based older adults
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DOI：10.1016/j.neurobiolaging.2026.05.007.png)
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Abstract
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• Brain arteriolosclerosis is associated with lower diffusion anisotropy • Brain arteriolosclerosis is associated with higher trace of the diffusion tensor • Diffusion anomalies are widespread but more pronounced in frontal lobe connections • Diffusion abnormalities are detectable even in mild arteriolosclerosis • Diffusion anomalies are more severe as arteriolosclerosis severity increases
Keywords:
Arteriolosclerosis
Brain
MRI
Diffusion
In-vivo
Pathology
Autopsy
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