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Disruption of carbon metabolism by the hepatic mononuclear phagocytic system drives liver injury in a mouse model of severe dengue
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DOI：10.1016/j.jhep.2026.06.045.png)
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Abstract
En 中文
• Severe dengue infection induced hepatic injury and disrupted carbon metabolism in murine models. • Altered cell–cell communication between hepatocytes and HMPS disrupted carbon metabolism. • Fostamatinib significantly suppressed liver injury progression. • Fostamatinib alleviated inflammation and restored carbon metabolic homeostasis in SD mice.
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33
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3.2W
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6.5W
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