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Distributed lag non-linear models with spatial effect modification using Laplacian P-splines

delete2026-06-25
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PRE
AI
S
Sara Rutten *
T
Thomas Neyens
E
Elisa Duarte
A
Antonio Gasparrini
DOI:10.1007/s10651-026-00739-0delete
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摘要

摘要

En 中文
分布式滞后非线性模型(DLNMs)是灵活建模时间延迟暴露效应的一种流行方法。经典DLNMs在地理区域间指定共同的暴露-滞后-响应关系。然而,这种关系可能因不同空间单元的差异效应修饰因子而被改变。尽管已提出一些处理效应修饰的方法,但其适用性具有情境依赖性。例如,元分析可以处理组间异质性,但该技术需要足够大的研究组。这一局限性在处理计数数据时尤为相关,因为事件数量往往较少。本文回顾了允许对基于计数的结局进行空间效应修饰的现有方法,并提出了一种贝叶斯DLNM替代方法,通过灵活的交互效应来考虑修饰因子。通过使用拉普拉斯P样条,我们避免了使用经典的马尔可夫链蒙特卡罗(MCMC)方法,提供了计算上更快速的估计过程。通过模拟研究评估了不同方法的性能。此外,通过包含87个意大利城市日温度和死亡计数的实际数据应用,展示了我们提出方法的实用性。
Keyword:
Bayesian P-splines
Distributed lag non-linear models
Laplace approximation
Spatial effect modification

期刊

Environmental and Ecological Statistics 封面图
Environmental and Ecological Statistics
IF:
1.8
论文数:
1.0K
被引数:
1.1K

机构

D
department of public health environments and society
学者数:
2
论文数: 1
被引数: 0
D
data science institute
学者数:
77
论文数: 42
被引数: 0
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