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DNA concentration analysis based on terahertz spectroscopy and a fourfold rotationally symmetric split-ring resonator metamaterial biosensor

delete2026-08-04
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PRE
AI
Y
Yubo Wu
赵
赵小燕 (Xiaoyan Zhao) *
T
Tianyi Bi
R
Rui Tao
M
Minghui Du
X
Xianhao Wu
Y
Yuehan Yang
Y
Yuan Yuan
T
Tianyao Zhang
R
Rui Zhang
Z
Zhaohui Zhang
P
Pei Yang
DOI：10.1016/j.sna.2026.118289delete
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Abstract

Abstract

En 中文
• Direct label-free detection of glioma-related IDH mutated DNA fragment concentrations. • 2.The resonance peak shift decreases near-proportionally with the reduction of sample concentration. • 3.A linear regression model was constructed with a coefficient of determination (R²) of 0.996. Based on the 3σ criterion, a theoretical limit of detection (LOD) as low as 1.99 pmol/mL was achieved.
Keywords:
DNA
Metamaterial Biosensor
Liquid biopsy
Resonance frequency shift
Terahertz Spectroscopy

Journal

Sensors and Actuators A-Physical cover
Sensors and Actuators A-Physical
IF:
4.9
Papers:
1.5W
Citations:
3.3W

Organization

U
university of science and technology
Scholars:
263
Papers: 121
Citations: 0
C
capital medical university
Scholars:
1.2W
Papers: 3.2K
Citations: 0
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