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Domain knowledge-driven encoder-decoder for nasopharyngeal carcinoma segmentation
DOI:10.1016/j.eswa.2024.125208.png)
摘要
En 中文
Accurate image segmentation is vital for the diagnosis and treatment of nasopharyngeal carcinoma (NPC). Although deep neural networks have shown promising performance in NPC segmentation, they depend on large-scale pixel-level annotation datasets for purely data-driven model training, which poses practical limitations. To address this challenge, this paper explores the domain knowledge, namely the expert knowledge from radiologists, and proposes a domain knowledge-driven encoder-decoder architecture. Specifically, the domain knowledge on image spatial information is formulated as Gaussian mixture distribution and then transformed into an optimal transport-based expert-prior regularization of the encoder, which enhances the model's ability in capturing discriminative features. To project the encoded features onto pixel space and obtain the segmentation maps, a cross-scale feature refinement module is built in the decoder with theoretical justification, which integrates the domain knowledge that radiologists segment NPC in a gradual refinement process. Experimental results verify the effectiveness of the proposed method for NPC segmentation. Remarkably, despite using only 10% of pixel-level annotation data, the domain knowledge-driven model outperforms recent deep neural networks that use the entire training data.
Keyword:
Domain knowledge
Image segmentation
Neural network
Nasopharyngeal carcinoma
期刊
IF:
7.5
论文数:
2.9W
被引数:
10.2W
机构
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