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Domain knowledge-driven encoder-decoder for nasopharyngeal carcinoma segmentation

delete2024-12-01
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PRE
AI
G
Geng-Xin Xu
C
Chuan-Xian Ren *
Y
Ying Sun
DOI:10.1016/j.eswa.2024.125208delete
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摘要

摘要

En 中文
Accurate image segmentation is vital for the diagnosis and treatment of nasopharyngeal carcinoma (NPC). Although deep neural networks have shown promising performance in NPC segmentation, they depend on large-scale pixel-level annotation datasets for purely data-driven model training, which poses practical limitations. To address this challenge, this paper explores the domain knowledge, namely the expert knowledge from radiologists, and proposes a domain knowledge-driven encoder-decoder architecture. Specifically, the domain knowledge on image spatial information is formulated as Gaussian mixture distribution and then transformed into an optimal transport-based expert-prior regularization of the encoder, which enhances the model's ability in capturing discriminative features. To project the encoded features onto pixel space and obtain the segmentation maps, a cross-scale feature refinement module is built in the decoder with theoretical justification, which integrates the domain knowledge that radiologists segment NPC in a gradual refinement process. Experimental results verify the effectiveness of the proposed method for NPC segmentation. Remarkably, despite using only 10% of pixel-level annotation data, the domain knowledge-driven model outperforms recent deep neural networks that use the entire training data.
Keyword:
Domain knowledge
Image segmentation
Neural network
Nasopharyngeal carcinoma

期刊

Expert Systems with Applications 封面图
Expert Systems with Applications
IF:
7.5
论文数:
2.9W
被引数:
10.2W

机构

S
shenzhen institute of advanced technology, cas
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5.6K
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被引数: 7
S
Sun Yat Sen University
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9.9W
论文数: 7.2W
被引数: 95
C
chinese academy of sciences
学者数:
56.7W
论文数: 45.0W
被引数: 704
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