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Donor management implications for high-sensitivity detection of low-level malaria parasitemia in blood donor screening

delete2026-06-22
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OA
AI
C
Carmen Charlton *
V
Valerie Conrod
D
Dilini Kumaran
C
Craig Jenkins
S
Sandy Shokoples
L
LeeAnn Turnbull
R
Ruwandi Kariyawasam
C
Chantale Pambrun
S
Steven J. Drews
DOI:10.1111/trf.70295delete
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Abstract

Abstract

En 中文
Transfusion-transmitted malaria can occur when donors have unrecognized asymptomatic infection with submicroscopic parasitemia, highlighting the need to detect low-level parasitemia in blood donor screening. However, these highly sensitive blood donor testing algorithms may refer donors to clinicians who use diagnostic algorithms with less analytical sensitivity. Here we describe the analytical sensitivity of a Health Canada (HC)/FDA approved blood donor screening test compared to commonly used diagnostic test algorithms.
Keywords:
laboratory testing
malaria
Plasmodium
public health
transfusion transmittable disease
validation
verification

Journal

Transfusion cover
Transfusion
IF:
2
Papers:
718
Citations:
1.3W

Organization

P
provincial public health laboratory alberta
Scholars:
3
Papers: 1
Citations: 0
C
Canadian Blood Services
Scholars:
516
Papers: 365
Citations: 464
U
university of alberta
Scholars:
5.0W
Papers: 4.9W
Citations: 64
S
surveillance and discovery laboratory
Scholars:
4
Papers: 1
Citations: 0
Cited Papers

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