.png){kind=icon}
返回
Dynamic clamp with StdpC software
.png){kind=icon}
OA
AI
DOI：10.1038/nprot.2010.200.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Dynamic clamp is a powerful method that allows the introduction of artificial electrical components into target cells to simulate ionic conductances and synaptic inputs. This method is based on a fast cycle of measuring the membrane potential of a cell, calculating the current of a desired simulated component using an appropriate model and injecting this current into the cell. Here we present a dynamic clamp protocol using free, fully integrated, open-source software (StdpC, for spike timing-dependent plasticity clamp). Use of this protocol does not require specialist hardware, costly commercial software, experience in real-time operating systems or a strong programming background. The software enables the configuration and operation of a wide range of complex and fully automated dynamic clamp experiments through an intuitive and powerful interface with a minimal initial lead time of a few hours. After initial configuration, experimental results can be generated within minutes of establishing cell recording.
Keyword:
ION CHANNELS
SYNCHRONIZATION
CELLS
MODEL
NEURONS
MODULATION
SIMULATION
INJECTION
GAIN
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
16
论文数:
4.0K
被引数:
5.6W
机构
引用论文
.png){kind=icon}
分享收藏分享收藏
分享收藏Barriers and facilitators of sports in children with physical disabilities: a mixed-method study肢体残疾儿童的运动障碍和促进者: 一项混合方法研究
PREAI
分享收藏
查看更多内容