.png){kind=icon}
返回
Dynamic light scattering optical coherence tomography
.png){kind=icon}
OA
AI
DOI：10.1364/OE.20.022262.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
We introduce an integration of dynamic light scattering (DLS) and optical coherence tomography (OCT) for high-resolution 3D imaging of heterogeneous diffusion and flow. DLS analyzes fluctuations in light scattered by particles to measure diffusion or flow of the particles, and OCT uses coherence gating to collect light only scattered from a small volume for high-resolution structural imaging. Therefore, the integration of DLS and OCT enables high-resolution 3D imaging of diffusion and flow. We derived a theory under the assumption that static and moving particles are mixed within the OCT resolution volume and the moving particles can exhibit either diffusive or translational motion. Based on this theory, we developed a fitting algorithm to estimate dynamic parameters including the axial and transverse velocities and the diffusion coefficient. We validated DLS-OCT measurements of diffusion and flow through numerical simulations and phantom experiments. As an example application, we performed DLS-OCT imaging of the living animal brain, resulting in 3D maps of the absolute and axial velocities, the diffusion coefficient, and the coefficient of determination. (C) 2012 Optical Society of America
Keyword:
BROWNIAN-MOTION
NONERGODIC MEDIA
FLOW
SYSTEMS
CORTEX
SIGNAL
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.3
论文数:
6.1W
被引数:
14.3W
机构
引用论文
分享收藏Three-dimensional ultrahigh resolution optical coherence tomography imaging of age-related macular degeneration.png)
OPTICS EXPRESS
OAAI
OPTICS EXPRESSIF3.3
OAAI分享收藏分享收藏
查看更多内容