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Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset

delete2026-08-10
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OA
AI
M
Michela Leocadi PhD, AFHEA *
N
Nicola Z. Hobbs PhD
M
Mena Farag MBBS, MRCP, PhD
M
Michael J. Murphy MB, BCh, BAO, MRCPI
K
Kate Fayer
O
Olivia Thackeray
H
Harry Knights MBBS, MRCP
J
James B. Rowe
T
Trevor W. Robbins CBE, FRS, FMedSci, FBPsS, FBPhS, PhD
B
Barbara J. Sahakian CBE, FBA, FMedSci, DSc, PhD, DipClinPsych
G
Geraint Rees BM, BCh, PhD, FMedSci
R
Rachael I. Scahill
S
Sarah J. Tabrizi CBE, MBChB, FRCP, PhD, FMedSci
C
Christelle Langley PhD, AFBPsS
DOI：10.1002/mds.70461delete
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Abstract

Abstract

En 中文
Longitudinal studies of seed-based functional connectivity (SBFC) in young adult Huntington's disease gene-expanded (HDGE) individuals are rare, and none, to our knowledge, have examined adult cohorts decades from predicted clinical motor diagnosis.
Keywords:
fMRI
Huntington's disease
seed-based functional connectivity
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Journal

Movement Disorders cover
Movement Disorders
IF:
7.6
Papers:
1.1W
Citations:
3.3W

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university of cambridge
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university college london
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