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Efficacy of intraoperative low dose intravenous Esketamine for acute postoperative pain control: Meta-analysis of randomized controlled trials
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DOI：10.1016/j.jclinane.2026.112278.png)
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Abstract
En 中文
• Low-dose intraoperative esketamine (<1 mg/kg) reduces acute postoperative pain. • Significant opioid-sparing effect observed up to 48 h post-surgery. • Decreases rescue analgesic use and intraoperative propofol consumption. • No increase in adverse events compared to control. • Supports esketamine as a safe adjunct for multimodal anesthesia.
Keywords:
Esketamine
Analgesia
Anesthesia
Opioids
Pain
Surgery
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