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Eldecalcitol enhances osteo/odontogenic differentiation and mineralized matrix formation via redox modulation in human dental pulp stem cells
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DOI：10.1016/j.tice.2026.103565.png)
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Abstract
En 中文
• Eldecalcitol regulates the stress–regeneration balance in human dental pulp stem cells. • Redox modulation by ELD determines cellular viability and differentiation outcomes. • Optimal ELD concentrations enhance osteo/odontogenic gene expression and mineralization. • Excessive concentrations increase oxidative stress and impair regenerative potential.
Keywords:
Eldecalcitol
Human dental pulp stem cells
Cytocompatibility
Osteogenic differentiation
Regenerative endodontics
Bioactivity
Mineralization
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