.png){kind=icon}
返回
Electrical antimicrobial susceptibility testing based on aptamer-functionalized capacitance sensor array for clinical isolates
.png){kind=icon}
OA
AI
DOI：10.1038/s41598-020-70459-3.png)
.png){kind=icon}
.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
To prescribe effective antibiotics to patients with bacterial infections in a timely manner and to avoid the misuse of antibiotics, a rapid antimicrobial susceptibility test (AST) is essential. However, conventional AST methods require more than 16 h to provide results; thus, we developed an electrical AST (e-AST) system, which provides results within 6 h. The proposed e-AST is based on an array of 60 aptamer-functionalized capacitance sensors that are comparable to currently available AST panels and a pattern-matching algorithm. The performance of the e-AST was evaluated in comparison with that of broth microdilution as the reference test for clinical strains isolated from septic patients. A total of 4,554 tests using e-AST showed a categorical agreement of 97% with a minor error of 2.2%, major error of 0.38%, and very major error of 0.38%. We expect that the proposed e-AST could potentially aid antimicrobial stewardship efforts and lead to improved patient outcomes.
Keyword:
GROWTH
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
3.9
论文数:
28.0W
被引数:
83.5W
机构
引用论文
分享收藏Single Cell Antimicrobial Susceptibility Testing by Confined Microchannels and Electrokinetic Loading.png)
ANALYTICAL CHEMISTRYOAAI
ANALYTICAL CHEMISTRYIF6.7
OAAI分享收藏Direct, rapid antimicrobial susceptibility test from positive blood cultures based on microscopic imaging analysisSCIENTIFIC REPORTSOAAI
SCIENTIFIC REPORTSIF3.9
OAAI分享收藏分享收藏
查看更多内容