.png){kind=icon}
返回
Electrical bioadhesive interface for bioelectronics
.png){kind=icon}
PRE
AI
DOI：10.1038/s41563-020-00814-2.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
Reliable functions of bioelectronic devices require conformal, stable and conductive interfaces with biological tissues. Integrating bioelectronic devices with tissues usually relies on physical attachment or surgical suturing; however, these methods face challenges such as non-conformal contact, unstable fixation, tissue damage, and/or scar formation. Here, we report an electrical bioadhesive (e-bioadhesive) interface, based on a thin layer of a graphene nanocomposite, that can provide rapid (adhesion formation within 5 s), robust (interfacial toughness >400 J m(-2)) and on-demand detachable integration of bioelectronic devices on diverse wet dynamic tissues. The electrical conductivity (>2.6 S m(-1)) of the e-bioadhesive interface further allows bidirectional bioelectronic communications. We demonstrate biocompatibility, applicability, mechanical and electrical stability, and recording and stimulation functionalities of the e-bioadhesive interface based on ex vivo porcine and in vivo rat models. These findings offer a promising strategy to improve tissue-device integration and enhance the performance of biointegrated electronic devices. A graphene nanocomposite hydrogel showing anisotropic swelling is used to realize an electrically conducting and removable bioadhesive that improves the mechanical and electrical integration of bioelectronics devices with wet dynamic tissues.
Keyword:
SENSOR
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
38.5
论文数:
6.8K
被引数:
11.5W
机构
暂无机构信息
引用论文
Tissue-adhesive wirelessly powered optoelectronic device for metronomic photodynamic cancer therapy
PREAI
分享收藏Coordinated State-of-Charge Control Strategy for Microgrid during Islanded Operation孤岛运行时微电网荷电状态协调控制策略
OAAI
OAAI分享收藏Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording.png)
SCIENCE ADVANCESOAAI
SCIENCE ADVANCESIF12.5
OAAI分享收藏Social Functioning in Predominantly Inattentive and Combined Subtypes of Children With ADHD多动症儿童的主要注意力不集中和合并亚型的社会功能OAAI
OAAI分享收藏Materials and Optimized Designs for Human-Machine Interfaces Via Epidermal ElectronicsADVANCED MATERIALS
OAAI
ADVANCED MATERIALSIF26.8
OAAI分享收藏Biodegradable and flexible arterial-pulse sensor for the wireless monitoring of blood flow用于无线监测血流的可生物降解和柔性动脉脉搏传感器
PREAI
分享收藏Ultrasoft electronics to monitor dynamically pulsing cardiomyocytes超软电子设备可监测动态脉动的心肌细胞NATURE NANOTECHNOLOGY
NATURE NANOTECHNOLOGYIF34.9
PREAI
分享收藏
查看更多内容