.png){kind=icon}
返回
Electrical resynchronization induced by direct His-bundle pacing
.png){kind=icon}
PRE
AI
DOI：10.1016/j.hrthm.2009.09.066.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
BACKGROUND Biventricular pacing (BiV) to effect cardiac resynchronization therapy can be technically difficult and fails to elicit a clinical response in 30% to 40% of patients. Direct His-bundle pacing (DHBP) theoretically could obviate some of these problems. Although DHBP is capable of narrowing the QRS in some patients, the consistency with which this can be achieved has not been characterized. OBJECTIVE The purpose of this study was to restore His-Purkinje functionality in consecutive patients undergoing de novo clinically mandated cardiac resynchronization therapy. METHODS DHBP was temporarily implemented at the time of implantation of a permanent BiV system in patients referred for cardiac resynchronization therapy. Native conduction, DHBP, and BiV QRS duration were compared. All patients presenting for BiV cardiac resynchronization therapy were eligible for the study. Ten patients were studied. RESULTS DHBP was successfully implemented in all 10 patients. In 7 of 10 patients, DHBP narrowed the QRS significantly compared with native conduction and BiV (mean QRS duration: native 171 +/- 13 ms, DHBP 148 +/- 11 ms, BiV 158 +/- 21, P <.0001). QRS narrowing with DHBP was specifically attributable to capture of latent His-Purkinje tissue. DHBP lead implantation time (16 minutes) was shorter than standard left ventricular lead implantation time (42 minutes). CONCLUSION DHBP was readily implemented in patients with standard indications for BiV cardiac resynchronization therapy. In most patients studied, DHBP resulted in a significantly narrower QRS compared with native conduction. DHBP may offer a physiologic alternative to BiV for cardiac resynchronization therapy.
Keyword:
Biventricular pacing
Cardiac resynchronization therapy
Conduction disease
Congestive heart failure
Device therapy
Direct His-bundle pacing
Electrical resynchronization
Physiologic pacing
AI总结
对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。
期刊
IF:
5.7
论文数:
9.7K
被引数:
1.6W
机构
引用论文
Para-Hisian pacing - A new method for differentiating retrograde conduction over an accessory AV pathway from conduction over the AV node.png)
CIRCULATION
CIRCULATIONIF38.6
PREAI
分享收藏The effect of cardiac resynchronization on morbidity and mortality in heart failure心脏再同步化对心力衰竭发病率和死亡率的影响
OAAI
OAAI分享收藏
查看更多内容