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Emerging roles of Dehydrogenase/Reductase (DHRS) in cancer
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DOI：10.1016/j.chemphyslip.2026.105590.png)
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Abstract
En 中文
• DHRS not only participates in the metabolism of lipids, steroids and retinol, but also plays a significant role in tumorigenesis and progression. • We conducted a comprehensive systematic review of DHRS members across diverse malignancies, elucidating their associations with clinical drug resistance and chemotherapy response biomarkers. • The role of DHRS has been elaborated from the aspects of metabolic reprogramming, classical signal pathways and clinical potentials.
Keywords:
DHRS
cancer
metabolic reprogramming
drug resistance
chemotherapy response
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