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Engineering challenges in cell-encapsulation technology
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DOI：10.1016/0167-7799(96)10021-4.png)
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摘要
En 中文
The use of implantable immunoisolation devices, in which the tissue is protected from immune rejection by enclosure within a semipermeable membrane or encapsulant, is one approach in the development of cell therapies, However, further research is required in the areas of: tissue supply from primary or cell-culture sources; maintenance of cell viability and function, its relationship to device design, and the role of, and factors affecting, oxygen-supply limitations; and, protection from immune rejection, especially in view of the mechanisms thought to operate in the presence of a semipermeable membrane, the properties of that membrane, and the implications for biology and device design.
Keyword:
TRANSPLANTATION
THERAPY
ISLETS
INVIVO
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