Environmental Factors Rather Than Genetics Likely Drive Vitamin D Deficiency in Idiopathic Scoliosis

I. Georgopoulos

doi:10.1016/j.spinee.2026.04.026

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Environmental Factors Rather Than Genetics Likely Drive Vitamin D Deficiency in Idiopathic Scoliosis

2026-04-23

I. Georgopoulos *

T. Cheng

D. Fell

A. Simony

M.O. Andersen

E. Einarsdottir

M.K. Karlsson

I. Bergström

E. Diarbakerli

N. Schizas

P. Gerdhem

DOI：10.1016/j.spinee.2026.04.026

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Abstract

En 中文

Low vitamin D levels in individuals with idiopathic scoliosis (IS) have been reported and suggested as a potential contributor to IS. Bone density has also been shown to be lower in individuals with IS.

Keywords:

Serum level of 25(OH)D

idiopathic scoliosis

polygenic risk score

bone metabolism

bone mineral density

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