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Epidemiologic Trends in Clostridioides difficile Infection Among U.S. Emergency Department Patients, 2014–2024
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DOI：10.1016/j.ajic.2026.07.002.png)
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Abstract
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• Emergency department Clostridioides difficile infection declined from 2014 to 2024. • Rates increased among adults aged 18 to 24 years despite overall decline. • Vancomycin use increased while metronidazole prescribing declined. • Fidaxomicin use increased after the 2021 guideline update. • Thirty-day emergency department revisits remained stable over time.
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