Epidural-related maternal fever and metabolomic changes: a pilot exploratory study

2026-06-17

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Minyu Zhang

Li Zhang

Dongyan Chen

Xiaodan Chen

Zhiqiang Yu

Jiangang Xu *

DOI：10.1016/j.ijoa.2026.105217

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• Preliminary data suggest maternal fever during labor involves systemic shifts rather than a single defect. • Early temperature elevation in parturients may be linked to altered lipid and amino acid metabolic networks. • Impaired heat dissipation and compromised antioxidant defenses may contribute to epidural analgesia fever.

Epidural-related maternal fever and metabolomic changes: a pilot exploratory study

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