.png){kind=icon}
返回
Evolving perspectives on rosetting in malaria
.png){kind=icon}
OA
AI
DOI：10.1016/j.pt.2022.08.001.png)
.png){kind=icon}
原文求助.png){kind=icon}
分享.png){kind=icon}
收藏
摘要
En 中文
The ability of the intraerythrocytic Plasmodium spp. to form spontaneous rosettes with uninfected red blood cells (URBCs) has been observed in the medically im-portant malaria parasites. Since the discovery of rosettes in the late 1980s, differ-ent formation mechanisms and pathobiological roles have been postulated for rosetting; most of which have focused on Plasmodium falciparum. Recent break-throughs, including new data from Plasmodium vivax, have highlighted the multi-faceted roles of rosetting in the immunopathobiology and the development of drug resistance in human malaria. Here, we provide new perspectives on the for-mation and the role of rosetting in malaria rheopathobiology.
Keyword:
FALCIPARUM-INFECTED ERYTHROCYTES
RED-BLOOD-CELLS
MEMBRANE PROTEIN-1 PFEMP1
HUMAN CEREBRAL MALARIA
PLASMODIUM-FALCIPARUM
CYTOADHERENCE CHARACTERISTICS
PARASITIZED ERYTHROCYTES
IN-VITRO
VIVAX
SEQUESTRATION
期刊
IF:
6.6
论文数:
3.1K
被引数:
8.2K
机构
引用论文
.png){kind=icon}
分享收藏
查看更多内容