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Exercise and GLUT4
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DOI：10.1249/JES.0000000000000224.png)
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The glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the sarcolemma and t-tubule and, over the longer term, total GLUT4 protein content. Here, we review key aspects of GLUT4 biology in relation to exercise, with a focus on exercise-induced GLUT4 translocation, postexercise metabolism and muscle insulin sensitivity, and exercise effects on GLUT4 expression.
Keyword:
exercise
GLUT4
insulin sensitivity
skeletal muscle
muscle
glucose
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