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Experience-dependent rapid structural changes in the human brain: A systematic review
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DOI：10.1016/j.neubiorev.2026.106736.png)
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Abstract
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• Human MRI studies reveal structural brain changes within 1-2 hours of experience. • DW-MRI and T1W-MRI capture short-term structural plasticity in task-relevant areas • Task duration and post-scan timing vary, limiting direct cross-study comparisons. • Vascular and metabolic confounds must be considered when interpreting changes. • Lifespan generalisability of rapid structural plasticity remains to be established. • Multimodal and temporally dense designs are needed to elucidate rapid plasticity mechanisms.
Keywords:
Rapid plasticity
structural MRI
T1-weighted imaging
diffusion weighted imaging
cortical thickness
gray matter volume
learning
neuroplasticity
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