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Exploring the link between a prior for active avoidance and apathy, anhedonia, and depression - a network analysis

delete2025-09-20
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AI
T
Tobias Granwald *
F
Federico Triolo
M
Máté Lengyel
P
Peter Dayan
M
Marc Guitart‐Masip *
DOI:10.1016/j.bpsc.2025.09.013delete
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Abstract

Abstract

En 中文
Learned helplessness has been suggested as a mechanism through which anhedonia in depression is developed. It has been theorised that this stems from a generalised pessimistic prior belief about the probability of success when attempting to actively avoid negative outcomes, thereby resulting in apathy and reduced motivation. Yet, how such a prior may relate to depression and apathy is unknown. Here, we leveraged a novel method based on cognitive tasks and Bayesian modelling to extract a reliable generalised prior expressing the probability with which negative outcomes are expected to be actively avoidable.
Keywords:
Network analysis
depression
Bayesian
Prior
Learned helplessness
Anhedonia
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Journal

Biological Psychiatry-Cognitive Neuroscience and Neuroimaging cover
Biological Psychiatry-Cognitive Neuroscience and Neuroimaging
IF:
4.8
Papers:
1.3K
Citations:
4.4K

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