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Exploring the link between a prior for active avoidance and apathy, anhedonia, and depression - a network analysis
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DOI:10.1016/j.bpsc.2025.09.013.png)
Abstract
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Learned helplessness has been suggested as a mechanism through which anhedonia in depression is developed. It has been theorised that this stems from a generalised pessimistic prior belief about the probability of success when attempting to actively avoid negative outcomes, thereby resulting in apathy and reduced motivation. Yet, how such a prior may relate to depression and apathy is unknown. Here, we leveraged a novel method based on cognitive tasks and Bayesian modelling to extract a reliable generalised prior expressing the probability with which negative outcomes are expected to be actively avoidable.
Keywords:
Network analysis
depression
Bayesian
Prior
Learned helplessness
Anhedonia
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